Wine is a compatibility layer to allow you to run Windows programs on Linux with near native efficiency. I use Wine to run foobar2000 on Linux. On Windows, foobar2000 supports upmixing stereo tracks into 5.1 surround sound. This was the first thing I missed when I moved my Desktop to Linux full time.
After a good bit of googling, it turns out that it is actually possible to pass 5.1 surround sound from a Wine application to the native Linux sound driver.
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